યુકેમાં રસી અપાયેલા લોકો (1)ધો dose): 46,689,242

People Vaccinated in the UK (2nd dose): 37,610,911

The COVID-19 vaccine made by Oxford University and AstraZeneca has been hailed as a triumph for British science. 

Brits started receiving the “game-changing” jab on 4 January 2021 – with millions more vaccinations expected throughout 2021. The vaccine is mainly being produced in the UK, though other sites across Europe are being used to manufacture the first doses of the jab.

Type
Viral vector (genetically modified virus)
Doses
2
અસરકારકતા
62-90%
NHS availability
Yes
Storage
Regular Fridge Temperature
MHRA Approval

30 December 2020

How does the Oxford University / AstraZeneca vaccine work in the body when taken?

Viral vector (genetically modified virus).

The COVID-19 virus uses proteins on its outer surface, called spike proteins, to enter the body’s cells and cause disease.

The vaccine is made up of another virus (of the adenovirus family) that has been modified to contain the gene for making the SARS-CoV-2 (COVID-19) spike protein (the part of the virus that allows it to enter human cells). The adenovirus itself cannot reproduce and does not cause disease.

Once it has been given, the vaccine delivers the SARS-CoV-2 gene into cells in the body. The cells will use the gene to produce the spike protein. The person’s immune system will treat this spike protein as foreign and produce natural defences − antibodies and T cells − against this protein.

If, later on, the vaccinated person comes into contact with SARS-CoV-2, the immune system will recognise the virus and be prepared to attack it: antibodies and T cells can work together to kill the virus, prevent its entry into the body’s cells and destroy infected cells, thus helping to protect against COVID-19.

What are the ingredients of the Oxford University / AstraZeneca vaccine?

One dose (0.5 ml) contains: COVID-19 Vaccine (ChAdOx1-S* recombinant) 5 × 10^10 viral particles.

*Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS CoV 2 Spike glycoprotein. Produced in genetically modified human embryonic kidney (HEK) 293 cells.

This product contains genetically modified organisms (GMOs).

અન્ય ઘટકો છે:

એલ હિસ્ટિડાઇન

ઇથેનોલ

સુક્રોઝ

પોલિસોર્બેટ 80

સોડિયમ ક્લોરાઇડ

ઇન્જેક્શન માટે પાણી

એલ-હિસ્ટિડાઇન હાઇડ્રોક્લોરાઇડ મોનોહાઇડ્રેટ

મેગ્નેશિયમ ક્લોરાઇડ હેક્સાહાઇડ્રેટ

ડિસોડિયમ એડેટેટ ડાયહાઇડ્રેટ

જો તમને ક્યારેય કોઈપણ ઘટકોને ગંભીર એલર્જીક પ્રતિક્રિયા આવી હોય તો તમારે રસી ન લેવી જોઈએ.

How is the Oxford University / AstraZeneca vaccine administered?

The vaccine is only being administered to people in a safe health care environment with facilities to treat allergic reactions if they do occur. Do not take the vaccine from anyone else. If offered by anyone, and you are in doubt, contact your GP.

The Oxford University / AstraZeneca vaccine is injected into a muscle (usually in the upper arm).

You will receive 2 injections. You will be told when you need to return for your second injection.

The vaccination course consists of two separate doses of 0.5ml each. The second dose should be administered between 4 and 12 weeks after the first dose.

It is recommended that individuals who receive a first dose of Oxford University / AstraZeneca vaccine should complete the vaccination course with the same vaccine.

During and after each injection of the vaccine, your doctor, pharmacist or nurse will watch over you for around 15 minutes to monitor for signs of an allergic reaction.

Are there any possible risks and/or side effects of the Oxford University / AstraZeneca vaccine?

Nothing in medicine comes without risks – even something we take without thinking, like paracetamol, may pose a risk.

બધી દવાઓની જેમ, આ રસી પણ આડઅસરો પેદા કરી શકે છે, તેમ છતાં દરેક જણ તેમને ન મળે. રસી સાથેના ક્લિનિકલ અધ્યયનમાં, મોટાભાગની આડઅસરો હળવાથી મધ્યમ પ્રકૃતિના હતા અને રસીકરણ પછીના કેટલાક અઠવાડિયામાં હજી કેટલાક હાજર હોવા સાથે થોડા દિવસોમાં ઉકેલાઈ ગયા હતા.

જો પીડા અને / અથવા તાવ જેવી આડઅસર મુશ્કેલીકારક હોય, તો પેરાસીટામોલવાળી દવાઓ લઈ શકાય છે. પરંતુ હંમેશાં પ્રથમ ડ doctorક્ટર સાથે વાત કરો.

 

Side effects can include:

Very common (may affect more than 1 in 10 people)

માથાનો દુખાવો

ઉબકા

Chills or feeling feverish

Tiredness

Generally feeling unwell

Muscle ache & joint pain

Tenderness

Swelling where injection is given

Bruising where injection is given

Itching

Pain

Redness

સામાન્ય (10 લોકો 1 પર 1 અસર કરી શકે છે)

Flu-like symptoms such as high temperature, sore throat, runny nose, cough and chills

A lump at the injection site

તાવ

Vomitting

અસામાન્ય (100 લોકોમાં 1 સુધી અસર થઈ શકે છે)

Feeling dizzy

Decreased appetite

Abdominal pain

Enlarged lymph nodes

Excessive sweating, itchy skin or rash

 

In clinical trials there were very rare reports of events associated with inflammation of the nervous system, which may cause numbness, pins and needles, and/or loss of feeling. However, it is not confirmed whether these events were due to the vaccine.

If you notice any side effects not mentioned here, please inform your doctor, pharmacist or nurse.

 

Warnings and Precautions

જો તમને આ રસી આપવામાં આવે તે પહેલાં તમારા ડ doctorક્ટર, ફાર્માસિસ્ટ અથવા નર્સ સાથે વાત કરો જો તમે:

If you have ever had a severe allergic reaction (anaphylaxis) after any other vaccine injection.

If you currently have a severe infection with a high temperature (over 38°C). However, a mild fever or infection, like a cold, are not reasons to delay vaccination.

If you have a problem with bleeding or bruising, or if you are taking a blood thinning medicine (anticoagulant).

જો તમારી રોગપ્રતિકારક શક્તિ યોગ્ય રીતે કાર્ય કરતી નથી (ઇમ્યુનોડેફિશિયન્સી) અથવા તમે એવી દવાઓ લઈ રહ્યા છો જે રોગપ્રતિકારક શક્તિને નબળી પાડે છે (જેમ કે ઉચ્ચ ડોઝ કોર્ટીકોસ્ટેરોઇડ્સ, ઇમ્યુનોસપ્રેસન્ટ્સ અથવા કેન્સરની દવાઓ).

Do NOT take the vaccine if

you have ever had a severe allergic reaction to any of the active substances or any of the other ingredient. Signs of an allergic reaction may include itchy skin rash, shortness of breath and swelling of the face or tongue. Contact your doctor or healthcare professional immediately or go to the nearest hospital emergency department right away if you have an allergic reaction. It can be life-threatening. 

જો તમને ખાતરી નથી કે ઉપરોક્તમાંથી કોઈ તમને લાગુ પડે છે, તો તમને રસી આપવામાં આવે તે પહેલાં તમારા ડ doctorક્ટર, ફાર્માસિસ્ટ અથવા નર્સ સાથે વાત કરો.

કોઈપણ રસીની જેમ, આ રસી તેને પ્રાપ્ત કરનારા તમામ લોકોનું સંપૂર્ણ રક્ષણ કરી શકશે નહીં.

No data is currently available in individuals with a weakened immune system or who are taking chronic treatment that suppresses or prevents immune responses.

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